MicroRNA-146a Improves Aortic Interstitial Cell Calcification by Regulating TLR4 / IRAK1 / TRAF6 / NF-?B Signaling Pathway

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100054849

Enrollment

Unknown

Registered

2021-12-28

Start date

2021-12-28

Completion date

Unknown

Last updated

2022-12-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aortic valve disease

Interventions

case series:Nil

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who underwent aortic valve replacement surgery in the Cardiovascular Surgery Department of our hospital from 2021 to 2022.

Exclusion criteria

Exclusion criteria: Patients with malignant tumors, low liver and kidney function, autoimmune diseases, rheumatic heart disease, and infective endocarditis.

Design outcomes

Primary

Measure	Time frame
Degree of aortic valve calcification;	—

Countries

China

Contacts

Public ContactFu Huaying

the Second Hospital of Tianjin Medical University

fuhuaying@tmu.edu.cn+86 13820406212

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026