Knee cartilage defect
Conditions
Interventions
Experimental group :Treatment of cartilage defects with granular cartilage
Control group:Treatment of cartilage defects by subchondral bone drilling
Sponsors
the 920th Hospital of the Chinese People's Liberation Army Joint Logistics Support Force
Eligibility
Sex/Gender
All
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1. The patient's gender is not limited, and the age is 18-60 years old; 2. According to the diagnostic criteria for knee osteoarthritis recommended by the American College of Rheumatology, the X-ray grading standard is graded according to SasaKit, which is in line with grades I-IV; 3. Before the start of the study, the subjects are willing and able to sign the informed consent form approved by the ethics committee; 4. Willing to cooperate closely with the strict postoperative rehabilitation procedures formulated by the doctor; 5. The patient himself is willing to cooperate with the whole treatment process, and is willing to bear the corresponding consequences or related complications after the treatment process, and the corresponding postoperative treatment measures; 6. According to the judgment of the researcher, the subjects can understand the clinical research and can cooperate to complete the whole research process; 7. The subject can read, express and understand the content of the research protocol, and can provide feedback in appropriate language; 8. No history of previous knee surgery.
Exclusion criteria
Exclusion criteria: 1. The patient is too obese, with a BMI index of >= 30kg/m^2; 2. X-leg or O-leg; 3. Known history of immune system disease and cause joint and meniscus damage; 4. Kellgren & Lawrence grade III and above arthritis with extensive damage to the meniscus; 5. Severe heart, liver, kidney and lung insufficiency; 6. Pregnant women and lactating women; 7. Known HIV-infected persons or drug addicts; 8. Bacterial infection of the knee joint cavity or septic arthritis; 9. To participate in another clinical study within 6 months; 10. Suffering from diseases that the researchers believe may affect their participation in this research, such as mental disorders, alcohol or drug addiction, malignant or serious illness, etc.; 11. The subject has other diseases and the life expectancy is less than 2 years; 12. The subjects are participating in other clinical trials and have not reached the endpoint; 13. Other patients considered by the investigator to be unsuitable to participate in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| BMI; | — |
Countries
China
Contacts
Public ContactTan Hongbo
the 920th Hospital of the Chinese People's Liberation Army Joint Logistics Support Force
Outcome results
None listed