The characteristics of ventilation strategies of the respiratory P-V curve were used to study the circulation changes during anesthesia induction

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100054842

Enrollment

Unknown

Registered

2021-12-28

Start date

2022-01-01

Completion date

Unknown

Last updated

2022-12-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory function

Interventions

control group:Routine respiratory management

experimental group: ventilation strategies based on the respiratory P-V curve

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with endotracheal intubation under general anesthesia; Aged 18-70 years; gender not limited; ASA I-III grade; cardiac function grade 1-3.

Exclusion criteria

Exclusion criteria: History of smoking, acute phase of respiratory tract infection, bronchiectasis, asthma, chronic obstructive pulmonary disease, history of cardiac surgery, history of cardiac interventional surgery, abnormal liver and kidney function.

Design outcomes

Primary

Measure	Time frame
peak airway pressure;Airway plateau pressure;Compliance;Oxygenation Index;Mean arterial pressure;per volume;Heart index;Myocardial contractility;	—

Secondary

Measure	Time frame
pH;Partial pressure of arterial oxygen;Partial pressure of arterial carbon dioxide;Partial pressure of venous carbon dioxide;Partial pressure of intravenous oxygen;heart rate;Urine output;lactic acid;Wake-up time;	—

Countries

China

Contacts

Public ContactWang Lin

Guangzhou Red Cross Hospital

wanglinzm2010@163.com+86 13450279021

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026