Idiopathic Oligoasthenoteratospermia
Conditions
Interventions
Control group:Placebo
Sponsors
Eastern Theater General Hospital
Eligibility
Sex/Gender
Male
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed with oligoasthenospermia according to the "World Health Organization Laboratory Manual for the Examination and Processing of Human Semen (Fifth Edition)"; 2. Abnormal semen quality in the initial examination and re-examination, meeting one of the following conditions: sperm density < 15 x 10^6/mL or total sperm count < 39 x 10^6, forward motile sperm ratio < 32% or total sperm motility The percentage of spermatozoa with normal morphology is less than 40%, and the total number of motile spermatozoa is more than 5 x 10^6.
Exclusion criteria
Exclusion criteria: 1. With testicular, epididymitis, prostatitis, severe genital trauma, testicular torsion, urinary tract infection, cryptorchidism, varicocele, and serious medical diseases such as diabetes, history of tumor, history of groin and genital surgery ; 2. Testicular volume 32; 4. Abnormal karyotype; 5. Patients with Yin deficiency and Fire Prosperity syndrome (clinical features: dry mouth and throat, five upsets and heat, prone to oral ulcers, slightly red and dry tongue); 6. Patients with endocrine diseases; 7. Exposure to occupational or environment with reproductive toxicity; 8. Medications to improve semen quality have been used in the past 2 weeks; 9. Hepatobiliary disease, severe renal insufficiency, clinical disease or medication history known to reduce fertility; 10. Known or suspected history of allergy to test drugs and similar products; 11. Any situation that the investigator believes may interfere with participation in the study or evaluation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total sperm count in forward motion; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sperm DNA fragmentation rate; | — |
Countries
China
Contacts
Public ContactYao Bing
Eastern Theater General Hospital
Outcome results
None listed