Cerebral vascular diseases
Conditions
Interventions
Sham-TMS group VS hot spot-TMS group VSfMRI Activation-TMS group:repeated Transcranial Magnetic Stimulation
Sponsors
The Affiliated Hospital of Hangzhou Normal University
Eligibility
Sex/Gender
All
Age
30 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged 30-80 years, the first onset, meets the diagnostic criteria for acute cerebral infarction, and has been diagnosed by imaging, and the course of the disease is within 3 months; 2. Dysphagia with WST grade III or above within 3 days after cerebral infarction; 3. Agree to carry out TMS treatment on the basis of conventional treatment and pass the TMS safety screening; 4. No previous epilepsy and other neuropsychiatric diseases, dysphagia caused by other neurological diseases or organic diseases, and no sedative drugs; 5. No contraindications to MRI scanning, no history of head trauma and severe heart disease; 6. Disorder of consciousness; 7. Inorganic infection or critical condition unable to cooperate with rehabilitation treatment 8. Can cooperate with the main test to complete the scale evaluation, MRI scan and TMS treatment; 9. Able to complete swallowing tasks and obtain activation points in bilateral cerebral cortex; 10. Amplitude of head movement for all fMRI images: maximum translation over 3.0 mm or maximum rotation 3.0 degree in any direction in x, y or z during the entire scan; 11. The structure of the mouth and throat is normal; 12. Right-handed.
Exclusion criteria
Exclusion criteria: 1. New clinical symptoms appear during treatment; 2. Can not tolerate TMS treatment; 3. The patient refuses to continue the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Swallowing function; | — |
Countries
China
Contacts
Public ContactChen Meiyuan
the Affiliated Hospital of Hangzhou Normal University
Outcome results
None listed