Knee osteoarthritis
Conditions
Interventions
experimental group:Flurbiprofen gel patch (gel patch)
control group:loxoprofen sodium cataplasm
Sponsors
Peking University Shougang Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. The selected patients are Chinese patients with knee osteoarthritis (KOA). Aged > 40 years; 2. The patient is diagnosed with knee osteoarthritis, has joint pain symptoms, and the VAS score recorded in the baseline period: 30mm <= VAS score <= 70mm; 3. Have not used any oral or topical non-steroidal analgesics and opioid analgesics within 1 week before enrollment; 4. No history of bleeding, asthma, severe heart, liver and kidney insufficiency, non-steroidal drug allergy, etc.; 5. Patients are willing and able to provide signed informed consent prior to any study-related procedures.
Exclusion criteria
Exclusion criteria: 1. Pregnant and lactating women or women of childbearing age who are about to conceive; 2. Patients who have participated in clinical studies of other drugs within 1 month; 3. Patients who have received intra-articular drug injection within 1 month; 4. Patients who have received hormone therapy within 1 month; 5. Have received knee or hip surgery within 3 months before enrollment, causing pain or affecting joint function; 6. Other concomitant diseases or complications that may affect the observation of the curative effect (local skin damage, infection; rash, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| pain VAS scores; | — |
Secondary
| Measure | Time frame |
|---|---|
| Knee WOMAC Score; | — |
Countries
China
Contacts
Public ContactGuan Zhenpeng
Peking University Shougang Hospital
Outcome results
None listed