Disorser of sleep-wake pattern on Alzheimer disease
Conditions
Interventions
Intervention group 1:Soundscape I intervention+Standard care
Control group:Standard care
Pre-test group:Experience a number of soundscape and evaluate
Intervention group 2:Soundscape II intervention+Standard care
Sponsors
Chongqing University
Eligibility
Sex/Gender
All
Age
50 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. The patient is willing to sign the informed consent form for the intervention experiment; 2. Use ICD-10 to determine whether the patient has symptoms of Alzheimer's disease. Use the Clinical Dementia Rating scale (CDR) to diagnose the degree of dementia (mild to severe) in patients; 3. Alzheimer's patients diagnosed with sleep disorders using the Pittsburgh Sleep Quality Index (PSQI); 4. Patients aged 50 years and above.
Exclusion criteria
Exclusion criteria: 1. Patients with major hearing impairment or severe auditory nerve damage; 2. Patients who have serious physical dysfunction, cardiovascular disease and other high-risk diseases; 3. Patients who participated in multiple intervention experiments at the same time; 4. Other reasons considered by the researchers are not suitable for the clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| percentage of amyloid-ß;Behavior Pathology in Alzheimer’s Disease Rating Scale;Chinese version of the neuropsychiatric inventory;percentage of Tau protein;Length of continuous sleeping time; | — |
Secondary
| Measure | Time frame |
|---|---|
| respiration rate;Heart rate;Body temperature;Frequency of stool;Behaviour observation;Soundscape evaluation;Diastolic blood pressure;Systolic blood pressure;Pittsburgh sleep quality questionnaire;Number of arousal time during sleeping;Beginning of the sleeping time; | — |
Countries
China
Contacts
Public ContactXie Hui
Chongqing University
Outcome results
None listed