Tuberculosis
Conditions
Interventions
Group 1:Take linezolid tablets 600 mg orally once daily
Group 2:Take contizolid tablets 800 mg twice daily.
Sponsors
Beijing Chest Hospital Affiliated to Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Newly treated pulmonary tuberculosis patients who have not taken anti-tuberculosis drugs; 2. 18-60 years old, male or female; 3. Sputum acid-fast bacilli smear 2+ or above, identified as rifampicin-sensitive or resistant Mycobacterium tuberculosis.
Exclusion criteria
Exclusion criteria: 1. Combined with severe cardiovascular, liver, kidney, nervous system, blood system and other diseases, combined with tumor diseases, extensive lesions and respiratory insufficiency; 2. Combined with diabetes and uncontrollable blood sugar; 3. HIV positive; 4. Patients with combined mental disorders; 5. Participate in other clinical trials; 6. Pregnant or lactating women; 7. Those who are allergic to the test drug; 8. According to the judgment of the investigator, the combined subjects are not suitable to participate in the clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Daily average decreased number of live bacteria; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse events / serious adverse events ;Vital signs;Blood and urine routine, liver and kidney function, ECG;Peripheral and optic neuropathy; | — |
Countries
China
Contacts
Public ContactGao Mengqiu
Beijing Chest Hospital Affiliated to Capital Medical University
Outcome results
None listed