Atopic dermatitis
Conditions
Interventions
Systemic therapy group:Nil
Sponsors
The Second Affiliated Hospital of Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Age
6 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Patients with AD who meet the Hanifin-Rajka diagnostic criteria (diagnostic criteria refer to: Hanifin JM, Rajka G. Diagnostic features of atopic dermatitis. Acta Dermatol Venereol (Stockh) 1980; 92:44-47); 2. Aged >= 6 years, male or female; 3. The disease severity reaches moderate to severe, that is, SCORAD score >= 25; 4. AD patients who will receive systematic treatment due to unsatisfactory previous topical drug therapy; 5. Obtain the consent of the patient or his/her guardian and sign the informed consent.=
Exclusion criteria
Exclusion criteria: 1. AD patients who had received excessive priuzumab therapy; 2. pregnant or breastfeeding women; 3. The known or suspected poor compliance could not complete the experimenter; The investigator judged that he was not suitable to participate in the clinical study; 4. Other AD patients not suitable for inclusion in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Scoring Atopic Dermatitis Index, SCORAD;Eczema area and severity index, EASI;Investigator's Global Assessment, IGA;VAS-NRS;ccl17;ccl18;ccl22;ccl26;ccl27;IL-18;periostin;granzyme B;TSLP; | — |
Secondary
| Measure | Time frame |
|---|---|
| Atopic Dermatitis Control Tool, ADCT;patient oriented eczema measure, POEM;dermatology life quality index, DLQI; | — |
Countries
China
Contacts
Public ContactZheng Min
The Second Affiliated Hospital of Zhejiang University School of Medicine
Outcome results
None listed