Non-Hodgkin’s lymphome
Conditions
Interventions
BGB group:received BGB regimen
Sponsors
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-60 years; 2. Gender: male or female; 3. Diagnosed as relapsed or refractory non-Hodgkin lymphoma; 4. Have indications for autologous hematopoietic stem cell transplantation; 5. The general condition is OK, and the ECOG score is less than or equal to 1 point; 6. Normal cardiac function: ejection fraction >= 50%; 7. Normal liver and kidney function: blood bilirubin<=35µmol/L, AST/ALT below 2 times the upper limit of normal, serum creatinine<=130µmol/L; 8. Subjects signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Has undergone autologous hematopoietic stem cell transplantation or allogeneic hematopoietic stem cell transplantation; 2. Serious bacterial and fungal infections were not controlled before transplantation; 3. Pregnant or breastfeeding women; 4. History of other malignant tumors other than hematological malignancies within 3 years; 5. Known infection with human immunodeficiency virus (HIV); 6. Other situations that do not meet the inclusion criteria.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| overall survival;recurrence-free survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| Implantation rate;Incidence of mucositis;transplant-related death; | — |
Countries
China
Contacts
Public ContactZhang Yicheng
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed