The analysis of factors influencing dental plaque microbiota in severe early childhood caries

The dental plaque microbiota of “relative healthy teeth” in children with severe early childhood caries

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100054715

Enrollment

Unknown

Registered

2021-12-25

Start date

2021-12-27

Completion date

Unknown

Last updated

2022-12-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary dental caries

Interventions

Case series:No

Eligibility

Sex/Gender

All

Age

3 Years to 5 Years

Inclusion criteria

Inclusion criteria: 1. Children aged 3-5 with caries and children without caries; 2. No less than 18 teeth; 3. Not wearing various orthodontic appliances and accessories; 4. No bacterial or viral infection in other parts of the body.

Exclusion criteria

Exclusion criteria: 1. Suffering from enamel hypoplasia or other oral diseases; 2. Fluoride, microecological regulators and immunosuppressants have been used within 3 months; 3. Those who have an oral orthodontic treatment plan within 6 months; 4. There are systemic diseases or congenital diseases.

Design outcomes

Primary

Measure	Time frame
Raw reads;	—

Secondary

Measure	Time frame
OTUs number;Alpha diversity index;Beta diversity index;	—

Countries

China

Contacts

Public ContactWu Li'an

School of Stomatology, the Fourth Military Medical University

1163647870@qq.com+86 29 84776083

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026