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Effect and mechanism of thunder-fire moxibustion combined with meibomian gland massage in patients with meibomian gland dysfunction

Effect and mechanism of thunder-fire moxibustion combined with meibomian gland massage in patients with meibomian gland dysfunction

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100054714
Enrollment
Unknown
Registered
2021-12-24
Start date
2018-09-01
Completion date
Unknown
Last updated
2022-12-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Meibomian gland dysfunction

Interventions

control group 1:meibomian gland massage
control group 2:0.1% fluorometholone eye drops
experimental group 1:meibomian gland massage
experimental group 2:thunder-fire moxibustion

Sponsors

Jinhua Traditional Chinese Medicine Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
25 Years to 66 Years

Inclusion criteria

Inclusion criteria: 1. Diagnostic criteria: The patient's eye symptoms: dry eye, eye pain, eye burning sensation, eye itching, foreign body sensation, scratching sensation, visual fluctuation, increased secretion, etc.; eyelid margin morphology changes: eyelid margin hypertrophy; Limbic telangiectasia and hyperemia; hyperkeratosis of the eyelid margin; irregular shape of the eyelid margin; meibomian gland opening higher than the eyelid margin or narrow or occluded; abnormal secretion of meibomian glands: the secretion of meibomian glands is cloudy and granular , toothpaste; missing meibomian glands; 2. Aged between 20 and 70 years old; able to cooperate with the operation; signed the informed consent form and participated voluntarily; followed up for 6 months.

Exclusion criteria

Exclusion criteria: 1. Patients with eye diseases such as conjunctivitis, keratitis, uveitis, scleritis, hordeolum, and meibomian gland cysts who are under treatment; incomplete eyelid structure, eyelid scars, local eyelid deformities, etc. caused by eye trauma; There are organic lesions such as mass in the eye; trauma, hemorrhage, skin infection or skin disease in the eye; acute glaucoma attack, fundus hemorrhage, etc.; 2. Allergic to any component of thunder fire moxibustion or surface anesthetic, fluorometholone eye drops, etc.; 3. Suffering from fever, severe cardiovascular and cerebrovascular diseases, infectious diseases, pregnant women, etc.; 4. Patients with a history of diabetes, arthritis, connective tissue, mental disorders, cognitive impairment, etc.; currently taking non-steroidal anti-inflammatory drugs or hormone drugs.

Design outcomes

Primary

MeasureTime frame
Interleukin 6;Prostaglandin E2;

Countries

China

Contacts

Public ContactQian Lijun

Jinhua Traditional Chinese Medicine Hospital

yingzhexuan2012@163.com+86 13757976984

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026