Retinitis pigmentosa
Conditions
Interventions
Experimental group:Peiyuan Mingmu Pills
Control group:Placebo
Sponsors
Eye Hospital, China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria of RP; 2. In line with TCM syndrome differentiation of liver and kidney yin deficiency; 3. Aged 18 to 80 years; 4. The best corrected visual acuity of at least one eye is greater than or equal to 35 letters (equal to 20/200 on the Snellen chart) detected by the ETDRS eye chart; 5. Agree to participate in this study and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Those who suffer from serious systemic diseases (such as cardiovascular and cerebrovascular, liver, hematopoietic system diseases, or serious life-threatening primary diseases, mental illness or cognitive impairment, etc.) affecting the research and follow-up; 2. People with other eye diseases: optic nerve and retinal diseases, glaucoma, ocular autoimmune diseases, ocular surface diseases affecting visual function, etc.; 3. Those who are judged by the investigator to be unable to provide reliable visual field test results in static or dynamic visual field tests; 4. Suspected liver and kidney insufficiency, such as laboratory test serum creatinine exceeds the upper limit of the normal value, ALT and AST exceed the normal value range by more than 2 times; 5. Participating in or participating in clinical trials of other drugs in the past 3 months, or using similar drugs in combination with other therapies that affect the evaluation of efficacy; 6. Those who are allergic to known components of the research drug; 7. Pregnant women and lactating patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual field; | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual acuity;Electroretinogram;Traditional Chinese Medicine syndrome scoring; Visual function questionnaire scoring; | — |
Countries
China
Contacts
Public ContactChao Guojun
Eye Hospital, China Academy of Chinese Medical Sciences
Outcome results
None listed