Head and neck squamous cell carcinoma (include nasopharyngeal carcinoma)
Conditions
Interventions
Control Group:None
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients with head and neck squamous cell carcinoma (including nasopharyngeal carcinoma) diagnosed by histopathology; 2. Aged 18 to 80 years; 3. Systemic functional status ECOG rating =100g/L, platelets >=80x10^9/L, white blood cell count >=3.0x10^9/L; 6. Sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Allergic to the probiotics of Streptococcus salivarius K12 or severe allergic constitution; 2. Poor compliance; 3. Pregnant or breastfeeding; 4. Any previous radiotherapy to the head and neck region; 5. Anti-mycotic/antiviral drugs within 1 week of treatment start; 6. Patients deemed unsuitable for the study by the investigator (concomitant with any serious other disease).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oral mucositis grade; | — |
Secondary
| Measure | Time frame |
|---|---|
| Taste function;Xerostomia;Quality of life;Adverse events; | — |
Countries
China
Contacts
Public ContactPeng Xingchen
West China Hospital, Sichuan University
Outcome results
None listed