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Effect of different loading doses of dexmedetomidine on intraoperative hemodynamics in patients undergoing laparoscopic cholecystectomy under general anesthesia

Effect of different loading doses of dexmedetomidine on intraoperative hemodynamics in patients undergoing laparoscopic cholecystectomy under general anesthesia

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100054687
Enrollment
Unknown
Registered
2021-12-24
Start date
2022-01-01
Completion date
Unknown
Last updated
2024-09-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cholecystitis

Interventions

Group C:Normal saline
Group L:Dexmeditomidine 0.5µg/mL
Group M:Dexmeditomidine 0.75µg/mL
Group H:Dexmeditomidine 1µg/mL

Sponsors

Sir Run Run Hospital Affiliated to Nanjing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing laparoscopic cholecystectomy under general anesthesia; 2. Patients with complete clinical records; 3. ASA grade I-III.

Exclusion criteria

Exclusion criteria: 1. Patients with a history of test drug allergy; 2. Patients with important system diseases such as heart, lung, liver, kidney, and blood; 3. Patients with communication or cognitive impairment; 4. Patients with respiratory tract infection symptoms of patients.

Design outcomes

Primary

MeasureTime frame
blood pressure;heart rate;—

Secondary

MeasureTime frame
awakening time;extubation time;consumption of anesthetics;nausea and vomiting;agitation;cough;visual analogue scale, VAS;—

Countries

China

Contacts

Public ContactYin Ning

Sir Run Run Hospital Affiliated to Nanjing Medical University

yinning882000@126.com+86 152 5175 7835

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026