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A positional and functional study on pathogenic genes in a family with systemic lupus erythematosus

A positional and functional study on pathogenic genes in a family with systemic lupus erythematosus

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100054681
Enrollment
Unknown
Registered
2021-12-23
Start date
2020-12-01
Completion date
Unknown
Last updated
2022-12-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Systemic lupus erythematosus

Interventions

Patient group:None
Health control group:None

Sponsors

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients with familial systemic lupus erythematosus: 1. The patient is from the same systemic lupus erythematosus family; 2. Comply with the 2019 EULAR/ACR SLE classification criteria; 3. Exclude rheumatoid arthritis, dermatomyositis, mixed connective tissue disease, etc.; 4. Agree to participate in this study and sign the informed consent. Familial systemic lupus erythematosus healthy controls: 1. Healthy controls are from the same systemic lupus erythematosus family as the patient; 2. No systemic disease; 3. Agree to participate in this study and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Coagulation disorders patients; 2. Hypertension patients; 3. Diabetics; 4. Smokers; 5. Pregnant women or nursing mothers; 6. Mental patients;

Design outcomes

Primary

MeasureTime frame
Single cell sequencing;—

Countries

China

Contacts

Public ContactGuo Qing

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

guoqingzsy@163.com+86 18922182868

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026