Cognitive disorders
Conditions
Interventions
Case series:None
Sponsors
Peking Union Medical College Hospital, Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Voluntarily sign the informed consent; 2. The patient aged >=18 years, primary school education level or above, and Chinese is the mother tongue; 3. Normal cognitive function: no complaints and medical history related to cognitive decline (referring to no clear or stable cognitive decline), and MMSE >= 26 points, and normal activities of daily living (Somatic Self-care Ability Scale and Instrumental Activities of Daily Living Scale total score <= 14 points); 4. Have the vision and hearing required to complete the cognitive test.
Exclusion criteria
Exclusion criteria: 1. Suffering from central nervous system diseases: history of stroke, Parkinson's disease or Parkinson's syndrome, traumatic brain dementia, intracranial space-occupying lesions (such as subdural hematoma, brain tumor), infection (such as encephalitis, syphilis) , AIDS, etc.), autoimmune encephalitis, multiple sclerosis, paraneoplastic syndrome, Creutzfeldt-Jakob disease, leukodystrophy, brain damage caused by other physical and chemical factors, etc.; 2. Important physical diseases (such as severe liver and kidney dysfunction, hepatic encephalopathy, pulmonary encephalopathy, advanced cancer, etc.), endocrine system diseases (such as thyroid disease, parathyroid disease) and metabolic factors such as vitamin deficiency; Patients with a history of alcohol or drug abuse during the year; 3. Psychiatric patients, according to DSM-IV-TR criteria, including schizophrenia or other mental illness, bipolar disorder, major depression or delirium.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognition; | — |
Countries
China
Contacts
Public ContactZhu Yicheng
Peking Union Medical College Hospital, Chinese Academy of Medical Sciences
Outcome results
None listed