Atopic Dermatitis
Conditions
Interventions
Experimental group:0.03% tacrolimus ointment
Control group:2% criborol ointment
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
2 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1. Aged 2 to 12 years, gender is not limited; 2. Patients with moderate atopic dermatitis diagnosed according to the Williams atopic dermatitis diagnostic criteria; 3. Have read the subject instructions, agree and sign the written informed consent.
Exclusion criteria
Exclusion criteria: 1. Those who are allergic to 0.03% tacrolimus ointment or 2% criborole ointment or have contraindications; 2. Local rash combined with viral, bacterial or fungal infection; 3. Patients with severe liver and kidney disease, blood system disease, autoimmune disease, chronic severe infection, diabetes, mental illness or malignant tumor and other serious diseases that may affect the correct evaluation of curative effect; 4. The withdrawal time of topical corticosteroids is less than 4 weeks; 5. The withdrawal time of systemic corticosteroids and other immunosuppressants (tripterygium wilfordii, etc.) is less than 12 weeks; 6. Other reasons considered inappropriate by the researcher, such as mental illness, communication disorder, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Localized Eczema Area and Severity Index Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Local Atopic Dermatitis Severity Score;Local Investigator Overall Score;Local Visual Analogue Scale pruritus score; | — |
Countries
China
Contacts
Public ContactLi Jingyi
West China Hospital of Sichuan University
Outcome results
None listed