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Effect of esmketamine on circulation during perioperative period

Effect of esmketamine on circulation during perioperative period

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100054608
Enrollment
Unknown
Registered
2021-12-21
Start date
2021-12-21
Completion date
Unknown
Last updated
2022-11-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Group A:????? 0.5mg/kg ????? 0.5mg/kg Esketamine 0.5mg/kg
Group B:Normal saline of the same dose

Sponsors

Guangzhou Red Cross Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Aged 20 to 70 years; 2. BMI 17.6~27.8 kg/m^2; 3. ASA I-III grade.

Exclusion criteria

Exclusion criteria: 1. Allergic to esketamine or propofol; 2. A history of addiction to opioids and esketamine.

Design outcomes

Primary

MeasureTime frame
Myocardial contractility;Radial Ascending Branch / Rise Time Max;Lung compliance;Veno-arterial carbon dioxide partial pressure difference;Mixed venous oxygen saturation;Postoperative cognitive function;Lactic acid;—

Countries

China

Contacts

Public ContactWang Lin

Guangzhou Red Cross Hospital

wanglinzm2010@163.com+86 13450279021

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026