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Efficacy and safety of asketamine combined with sufentanil in subanesthesia for analgesia in hip arthroplasty

Efficacy and safety of asketamine combined with sufentanil in subanesthesia for analgesia in hip arthroplasty

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100054599
Enrollment
Unknown
Registered
2021-12-20
Start date
2021-07-01
Completion date
Unknown
Last updated
2022-11-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Artificial hip replacement

Interventions

Experimental group:esketamine

Sponsors

Army Medical Center of PLA
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 40 to 75 years who are planning to undergo elective hip replacement; 2. American Society of Anesthesiologists (ASA) Grade I ~ II; 3. Agree to enter the study and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. With cognitive dysfunction or poor understanding ability, unable to communicate effectively; 2. Have a history or family history of mental disorders; 3. Recent use of narcotic analgesia, sedation, anti-anxiety or depression drugs; 4. Patients with uncontrolled hypertension, history of cerebrovascular accidents, increased intracranial pressure, and intracranial space occupying lesions; Glaucoma, hyperthyroidism, acute alcoholism or chronic addiction; 5. Allergic to local anesthetics or infected persons at the intended puncture site; Coagulation dysfunction; Allergic to sufentanil or esketamine.

Design outcomes

Primary

MeasureTime frame
visual analogue scale;

Countries

China

Contacts

Public ContactYan Hong

Army Medical Center of PLA

cqyanhong@163.com+86 13638319969

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026