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The effect and neural mechanism of pharyngeal sensory electrical stimulation on patients with chronic severe neurogenic dysphagia

The effect and neural mechanism of pharyngeal sensory electrical stimulation on patients with chronic severe neurogenic dysphagia

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100054548
Enrollment
Unknown
Registered
2021-12-19
Start date
2021-12-20
Completion date
Unknown
Last updated
2022-11-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

dysphagia

Interventions

Experimental group:Pharyngeal sensory electrical stimulation
Control group:False pharyngeal sensory electrical stimulation

Sponsors

The Third Affiliated Hospital of Sun Yat-Sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 18 to 80 years who are hospitalized with central nervous system diseases such as cerebral infarction, cerebral hemorrhage, and traumatic brain injury; 2. FOIS score 1-2; 3. The vital signs are stable, and there is no serious heart or lung disease; 4. There was no significant improvement in swallowing function after 1 month of routine swallowing rehabilitation; 5. There is no hearing comprehension disorder, and the treatment can be cooperated; 6. The patient or legal representative signed the informed consent.

Exclusion criteria

Exclusion criteria: 1. Severe cognitive impairment (MMSE <13 points), severe aphasia; 2. Vocal cord tremor, spasm, and significantly limited abduction; 3. Pacemaker or implantable cardiac defibrillator, unstable cardiopulmonary status, severe arrhythmia, etc.; 4. Oropharyngeal anatomical structure distortion, head and neck tumors; 5. Combined with esophageal perforation, esophageal stenosis, esophageal diverticulum, gastric ulcer bleeding, esophageal varices; 6. Patients who cannot cooperate with the evaluation of FEES, HRM, VFSS, fNIRs, etc.; 7. Women who are pregnant, planning to become pregnant or breastfeeding.

Design outcomes

Primary

MeasureTime frame
functional oral food intake scale;

Secondary

MeasureTime frame
Leakage Aspiration Score;Murry secretion scale;Yale residue classification scale;Hypopharyngeal peak pressure;

Countries

China

Contacts

Public ContactWen Hongmei

The Third Affiliated Hospital of Sun Yat-Sen University

wenhm0625@126.com+86 18922103172

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026