Non-variceal upper gastrointestinal bleeding
Conditions
Interventions
Experimental group:Ilaprazole intravenous drip
Control Group:esomeprazole intravenous drip
Sponsors
Affiliated Hospital of Qingdao University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Males or non-pregnant females aged 18 to 70 years; 2. Symptoms of upper gastrointestinal bleeding, such as vomiting blood, blood in the stool or black stools, occur within 48 hours; 3. ANVUGIB is diagnosed by gastroscopy, but endoscopic hemostasis may not be performed.
Exclusion criteria
Exclusion criteria: 1. Intravenous injection of two or more PPIs within 24 hours before enrollment; 2. Intolerance of endoscopic diagnosis; variceal bleeding; 3. Allergic to proton pump inhibitors.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| clinical hemostasis rate on the 3rd day; | — |
Secondary
| Measure | Time frame |
|---|---|
| clinical hemostasis rate on the 5th day;average blood transfusion volume;overt rebleeding on the 7th day;length of hospital stay; | — |
Countries
China
Contacts
Public ContactTian Zibin
Affiliated Hospital of Qingdao University
Outcome results
None listed