Heart Failure
Conditions
Interventions
Control group:Optimized medication for heart failure + intravenous infusion of normal saline 50 ml
Experimental group:Optimized medication for heart failure + intravenous infusion of umbilical cord blood mononuclear cells
Sponsors
Shandong Provincial Third Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Clinically diagnosed patients with heart failure caused by ischemic cardiomyopathy; 2. NYHA cardiac function class III-IV; 3. Subjects who have been treated with optimized heart failure drugs, but the symptoms of heart failure are still uncontrolled; 4.6-minute walking test, the walking distance is less than or equal to 150 meters; 5. Echocardiography suggests left ventricular ejection fraction EF= 1800 pg/ml. 7. Aged >= 18 years, gender is not limited; 8. Voluntarily signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Past or current tumor history or other fatal diseases that may affect short-term survival; 2. Active infection; 3. There was hemodynamic instability and shock.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mortality;Rate of re-hospitalization;6 minutes walking test;Left ventricular end diastolic diameter; | — |
Secondary
| Measure | Time frame |
|---|---|
| Plasma B type natriuretic peptide; | — |
Countries
China
Contacts
Public ContactGao Dongxue
Shandong Province Third Hospital
Outcome results
None listed