gingival inflammation
Conditions
Interventions
Experimental group:GUM Dental mouthwash
Control group:Placebo
Sponsors
Affiliated Stomatological Hospital of Nanjing University School of Medicine
Eligibility
Sex/Gender
All
Age
20 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. There are more than 20 detectable teeth (including 11, 16, 17, 26, 27, 31, 36, 37, 46, 47, except the third molar); 2. Aged 20 to 70 years, and the gender is not limited; 3. Subjects should have an appropriate degree of gingivitis; BI (Bleeding Index Mazza, 1981) was enrolled with a baseline index value of 1.0-3.0; 4. Non-smokers (including e-cigarettes) (refers to those who have no smoking history or who have quit smoking); 5. Subjects voluntarily agreed to participate in this trial and signed the subject's informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients who are allergic or have a history of allergy to cetylpyridinium chloride (CPC), dipotassium glycyrrhizinate (GK2), tranexamic acid (TXA), and sodium fluoride (NaF); 2. Those who used antibiotics and other mouthwashes within one month before participating in the study; 3. Periodontal treatment within 3 months; 4. Patients with open caries or mucosal lesions in the oral cavity or patients with severe periodontitis; 5. Uncontrolled systemic disease; 6. undergoing chemotherapy or having a history of malignant tumor; 7. Undergoing orthodontic treatment; 8. Pregnant or lactating women or have a childbearing plan in the past 3 months; 9. Participate in other clinical trials within three months before screening; 10. Subjects who are deemed unsuitable by the investigator to participate in this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction rate of gingival inflammation; | — |
Countries
China
Contacts
Public ContactLi Yanfen
Affiliated Stomatological Hospital of Nanjing University School of Medicine
Outcome results
None listed