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Tolerability and Pharmacokinetics of KH906 in Single/Multiple Dosing in Healthy Subjects

Tolerability and Pharmacokinetics of KH906 in Single/Multiple Dosing in Healthy Subjects

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100054501
Enrollment
Unknown
Registered
2021-12-18
Start date
2021-12-13
Completion date
Unknown
Last updated
2022-11-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neovascular (wet) age-related macular degeneration

Interventions

Experimental group:kh906

Sponsors

West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 45 years, both male and female, and the BMI (weight (Kg)/height (m) square) is 19 to 24; 2. Qualified in the comprehensive physical examination, with normal blood and urine routine, liver and kidney function tests and electrocardiogram, and negative hepatitis B surface antigen; 3. Voluntarily take the test after understanding the content of the test, and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Those with a history of drug and food allergies, allergic diseases or allergic constitution; 2. Those with a history of chronic or organic diseases or existing heart, liver, kidney and blood system diseases; 3. Participated in other drug trials within 2 months before the trial; 4. Those who have participated in blood donation within 3 months before the test; 5. Those who have used any medicine (including traditional Chinese medicine) within 2 weeks; 6. Those who regularly take drugs, drink alcohol or smoke; 7. Those with poor compliance.

Design outcomes

Primary

MeasureTime frame
tolerance;

Secondary

MeasureTime frame
plasma drug concentration;

Countries

China

Contacts

Public ContactShen Qi

West China Hospital of Sichuan University

769824157@qq.com+86 28 85423837

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026