A randomized controlled non-inferiority study of mvarolysis and arthroscopic release in the treatment of refractory joint adhesions after knee surgery

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100054481

Enrollment

Unknown

Registered

2021-12-18

Start date

2022-01-01

Completion date

Unknown

Last updated

2022-11-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Arthrofibrosis after knee surgery

Interventions

Group 1:manipulation under anesthesia

Group 2:lysis of adhesions

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. 12-24 weeks after unilateral knee surgery; 2. Active knee flexion < 110 degrees; 3. Limited knee extension < 5 degrees.

Exclusion criteria

Exclusion criteria: 1. Postoperative joint infection; 2. Heterotopic ossification, graft dislocation or prosthesis loosening; 3. Affected knee combined with other joints (hip or ankle) injury of lower extremity; 4. The contralateral knee has a history of injury or surgery; 5. There are other diseases that affect the function of the lower limbs; 6. Re-adhesion after arthroscopic release.

Design outcomes

Primary

Measure	Time frame
Knee flexion;	—

Secondary

Measure	Time frame
International Knee Documentation Committee Subjective Knee Assessment Form;Lysholm Knee Rating Scale;	—

Countries

China

Contacts

Public ContactCai Bin

Ninth People's Hospital Affiliated to Shanghai Jiaotong University School of Medicine

shrehab@163.com+86 15618738497

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026