Malignant tumor, peripheral nerve disease
Conditions
Interventions
2Hz EA Group:2Hz Electroacupuncture
100Hz EA Group:100Hz Electroacupuncture
2/100Hz EA Group:2/100Hz Electroacupuncture
Control Group:Oral methylcobalamin tablets, 1 tablet/time, 3 times a day for 4 weeks
Sponsors
Zhejiang Cancer Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged above 18 years old but below 70 years old, the expected survival time is >= 1 year; 2. Pathologically diagnosed as malignant tumor, with more than 1 peripheral neurotoxicity after chemotherapy with platinum, paclitaxel and vinblastine drugs; 3. Have the ability of daily living, no hearing loss, and be able to complete various examinations independently; 4. No serious heart, liver, brain, kidney and other diseases, Karnofsky functional status score (KPS)> 60; 5. Clear consciousness, no mental illness or cognitive impairment; 6. Able to sign the written informed consent for clinical trials.
Exclusion criteria
Exclusion criteria: 1. Suffering from serious systemic diseases (cardiovascular disease, acute infectious diseases, blood diseases, endocrine diseases, allergies or hemoptysis); 2. Suffering from peripheral neuropathy caused by other causes, such as peripheral nerve injury or diabetic peripheral neuropathy; 3. Pregnant and lactating patients; 4. Alcohol and/or other drug abuse or dependence; 5. Participate in other clinical trials of acupuncture or drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patient peripheral neurotoxicity self-assessment questionnaire;Peripheral neurotoxicity assessment grade; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life scale;Nerve conduction velocity measurement; | — |
Countries
China
Contacts
Public ContactLu Chao
Zhejiang Cancer Hospital
Outcome results
None listed