None listed
Conditions
Interventions
Control group:Propofol
Sponsors
Affiliated Hospital of Chengdu University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 65 years, both male and female; 2. Body mass index (BMI): >=18 and <= 30kg/m2; 3. Patients undergoing painless gastroscopy; 4. American Anesthesiologist Classification (ASA) I-II; 5. Be able to understand the research process and methods, and voluntarily participate in this research.
Exclusion criteria
Exclusion criteria: 1. Those with contraindications to general anesthesia or those who have had a history of anesthesia accident in the past; 2. Known or suspected allergies or contraindications to propofol injection, cyclopofol injection excipients, benzodiazepines, opioids, muscle relaxants, etc.; 3. Combined with craniocerebral loss, intracranial hypertension, stroke, unstable angina, myocardial infarction; 4. Respiratory insufficiency, obstructive pulmonary disease, difficult airway, or tracheal intubation is judged to be difficult (modified Markov score is grade III or grade IV); 5. Uncontrolled diabetes or high blood pressure; 6. Insufficient fasting time (fasting 30 severely obese; 10. Severe neurological disease, unable to cooperate with the examination (such as acute stroke, convulsion, epilepsy not effectively controlled); 11. Those with a history of oropharyngeal surgery or with swallowing dysfunction before surgery; 12. Those who have participated in any drug clinical trials within 1 month before screening; 13. Those with allergies to sedative/anesthetic drugs and other serious anesthesia risks; 14. Patients with nasal polyps, nasal bleeding tendency, nasal trauma, nasal deformity, nasal inflammation, etc.; patients with a history of mandibular joint dislocation or mandibular injury.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Positive rate of pharyngeal refle; | — |
Secondary
| Measure | Time frame |
|---|---|
| Glottis motion;Exposure of tracheal cartilage retroglottic;The Dysphagia Severity Score;The Penetration and Aspiration Scale; | — |
Countries
China
Contacts
Public ContactWang Xiong
Affiliated Hospital of Chengdu University
Outcome results
None listed