Periorbital hyperpigmentation (pigmented dark circles)
Conditions
Interventions
Experimental group:Laser and injection of PRP
Sponsors
The Fifth Affiliated Hospital of Sun Yat-Sen University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients with pigmented dark circles or mixed dark circles dominated by pigmented type; 2. Fitzpatrick's skin types are type II, type III or type IV; 3. Aged 18 to 65 years; 4. Voluntarily sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Any signs of eye infection or inflammation; 2. Have used photosensitizing drugs or performed periocular injection and surgery in the past 12 months; 3. Platelet count < 150 x 10^9/L; 4. Before treatment and within 4 weeks after treatment, exposure to the sun cannot be avoided; 5. Pregnant and lactating women; 6. Suffering from other skin diseases, blood system diseases, serious chronic diseases, such as chronic renal failure, liver insufficiency/hepatitis, cardiovascular disease, diabetes, thyroid disease, cancer, chronic inflammatory diseases (such as lupus erythematosus, scleroderma disease, dermatomyositis, vasculitis, inflammatory bowel disease, rheumatoid arthritis, etc.); 7. History of keloid formation; 8. Taking non-steroidal anti-inflammatory drugs, steroid hormones, anticoagulants; 9. Patients with unrealistic expectations; 10. Those who are allergic to thrombin, calcium gluconate and lidocaine.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual analogue scale (VAS) score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Investigator overall assessment;Degree of suborbital pigmentation;Sadick lacrimal sulcus rating scale;Overall satisfaction score; | — |
Countries
China
Contacts
Public ContactMa Han
The Fifth Affiliated Hospital of Sun Yat-Sen University
Outcome results
None listed