Nerve block
Conditions
Interventions
Experimental group1:0.375% ropivacaine combined with 0.5ug/kg dexmedetomidine
Experimental group2:0.375% ropivacaine combined with 0.75ug/kg dexmedetomidine
Experimental group3:0.375% ropivacaine combined with 1.0ug/kg dexmedetomidine
Sponsors
Nanfang Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 65 years (including 18 years old and 65 years old); 2. Elective forearm or hand surgery at BPB; 3. ASA I~II patients; 4. Patients who agree to participate in this study and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Pregnant or lactating women; 2. Bleeding tendency or coagulation dysfunction; 3. History of allergy to local anesthetics, skin infection at the puncture site or contraindications of coexisting regional anesthesia; 4. Combined with serious primary diseases such as lung, liver, kidney, cardiovascular and hematopoietic system; 5. The patient cannot read, understand and communicate; 6. History of subclavian fossa surgery, nerve injury or neurological disease; 7. Those who have participated in clinical trials of other drugs within the past 3 months; 8. The researcher judges that it is not suitable to participate in this research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Onset time of sensory block;Onset time of motor block;Duration of sensory block;Duration of motor block; | — |
Secondary
| Measure | Time frame |
|---|---|
| Vital signs; | — |
Countries
China
Contacts
Public ContactLin Chunshuui
Nanfang Hospital
Outcome results
None listed