Digestive system diseases
Conditions
Interventions
Group N:Nalbuphine 0.1mg/kg
Sponsors
The First Affiliated Hospital of Anhui Medical Univercity
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing elective painless gastroscopy, ASA I-III grades; 2. Aged 60-80 years; 3. BMI 18-24 kg/m^2; 4. Communication is normal; 5. Voluntarily test and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Severe respiratory and circulatory system diseases: such as severe coronary heart disease, chronic obstructive pulmonary disease, etc.; 2. Endocrine system diseases: such as pituitary tumor, severe diabetes, hypercortisol syndrome, pheochromocytoma, etc.; 3. Mental and psychological diseases: such as schizophrenia, depression, history of chronic analgesic drug use, history of alcoholism, opioid dependence; 4. History of allergy to anesthetics.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Median effective dose;Orientation recovery time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Dosage of Remimalolam;Dosage of Nalbuphine;Recovery time;Duration time given initial dose of remimalolam;Respiratory depression;Adverse reactions;Duration of procedure;Ramsay sedative score;Hemodynamic parameters; | — |
Countries
China
Contacts
Public ContactTang Lili
The First Affiliated Hospital of Anhui Medical University
Outcome results
None listed