Atopic dermatitis
Conditions
Interventions
Experimental Group:Sequential topical application of mometasone furoate cream and crisaborole ointment
Control Group:Sequential topical application of mometasone furoate cream and emollients
Sponsors
Children's Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
2 Years to 17 Years
Inclusion criteria
Inclusion criteria: 1. Children with atopic dermatitis who meet the criteria of Hanifin and Rajka; 2. Aged 2-17 years; 3. Disease severity: EASI<=21 points, IGA<=3 points; 4. Informed consent, voluntary principle, families who agree to participate in the research; 5. Not participating in other clinical research projects.
Exclusion criteria
Exclusion criteria: 1. Receive non-steroidal immunosuppressants (such as cyclosporine, methotrexate) or ultraviolet therapy or systemic glucocorticoid therapy within 4 weeks before enrollment; 2. Suffering from serious infectious diseases, mental diseases, primary or secondary immune deficiencies, tumors, etc.; 3. The guardian suffers from mental illness, abnormal consciousness, cognitive impairment, etc.; 4. Unable to follow the doctor's order regularly; 5. Children allergic to mometasone furoate cream and/or criborole ointment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Investigator's overall rating;Eczema area and severity index score;Adverse reaction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient-directed eczema measurements;Pruritus numerical scale; | — |
Countries
China
Contacts
Public ContactWang Hua
Children's Hospital Affiliated to Chongqing Medical University
Outcome results
None listed