non-small cell lung cancer (NSCLC)
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. It is planned to undergo unilateral segmental or lobectomy with elective one-lung ventilation; 2. Aged 18-80 years; 3. ASA classification I-III; 4. Agree to sign the informed consent form before this study.
Exclusion criteria
Exclusion criteria: 1. Severe COPD, the preoperative pulmonary function test shows that the forced expiratory volume in the first second (FEV1) is less than 50% of the predicted value; 2. History of previous thoracic surgery or radiotherapy, known pleural or interstitial lesions; 3. Active pulmonary infection or mass in the main bronchus; 4. The application of PEEP is contraindicated (high intracranial pressure, bronchopleural fistula, etc.); 5. Severe asthma; 6. Difficult airway; 7. Body mass index > 30kg/m^2; 8. The patient refused to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence and severity of postoperative pulmonary complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| The quality and speed of lung collapse;Mechanical ventilation and oxygenation parameters;Malposition of airway tools;Hospital length of stay;Other complications; | — |
Countries
China
Contacts
Beijing Friendship Hospital Affiliated to Capital Medical University