chronic endometritis (CE)
Conditions
Interventions
Case group:None
Control group:None
Sponsors
The Second Affiliated Hospital of South China University
Eligibility
Sex/Gender
Female
Age
20 Years to 49 Years
Inclusion criteria
Inclusion criteria: 1. Case group inclusion criteria: (1) Subjects between the ages of 20 and 49; (2) Sign the informed consent; (3) Those who have no cognitive impairment, can understand the content of the questionnaire, and cooperate with biological specimen collection and follow-up; (4) No abnormality in pathological examination and leucorrhea examination, and the positive immunohistochemistry of endometrial tissue for CD138/CD38 was diagnosed as chronic endometritis; (5) No gynecological tumors or other malignant diseases such as uterine fibroids, adenomyosis, ovarian cancer and cervical cancer; (6) Non-menstrual period; (7) No history of diabetes, hypertension, hyperlipidemia, immune system diseases, sexually transmitted diseases, serious heart, brain, liver and other diseases; (8) No history of taking antibiotics, hormones, immunosuppressants or taking Mirena in the past month. 2. Inclusion criteria for the control group: (1) Subjects between the ages of 20 and 49; (2) Sign the informed consent; (3) Those who have no cognitive impairment, can understand the content of the questionnaire, and cooperate with the collection of biological specimens; (4) Immunohistochemical negative for CD138/CD38 in endometrial tissue and no abnormality in pathological examination and B-ultrasound examination; (5) No vaginitis, endometritis, uterine fibroids, adenomyosis, ovarian cancer and cervical cancer and other gynecological uterine inflammatory diseases, gynecological tumors or other malignant diseases; (6) Regular menstruation, currently in non-menstrual period, non-contraceptive period, no vaginal douching and no uterine cavity operation within six months; (7) No history of diabetes, hypertension, hyperlipidemia, immune system diseases, sexually transmitted diseases, serious heart, brain, liver and other diseases; (8) No history of taking antibiotics, hormones, immunosuppressants or taking Mirena in the past month.
Exclusion criteria
Exclusion criteria: Subjects with missing essential or important data.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| inflammatory factors;microorganisms;blood routine examination;ESR;C-reactive protein;coagulation function ;six sex hormones; | — |
Countries
China
Contacts
Public ContactGao Hong
The Second Affiliated Hospital of South China University
Outcome results
None listed