A cohort study of nutritional factors and colorectal cancer with sarcopenia

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100054301

Enrollment

Unknown

Registered

2021-12-13

Start date

2022-01-01

Completion date

Unknown

Last updated

2022-11-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

colorectal cancer

Interventions

Colorectal cancer with sarcopenia group:None

Colorectal cancer without sarcopenia group:None

Colorectal cancer combined with malnutrition group:None

Colorectal cancer without malnutrition group:None

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Case-control study: (1) Patients diagnosed with colorectal cancer for the first time in the Affiliated Hospital of Southwest Medical University during 2020.01-2021.12; (2) Aged 18-80 years; (3) The first confirmed diagnosis of colorectal cancer by clinical examination; (4) Enhanced abdominal CT examination should be completed within two weeks before and after admission. 2. Cohort study: (1) Patients who were diagnosed with colorectal cancer for the first time in the Affiliated Hospital of Southwest Medical University from 2022.01 to 2022.06 and planned to undergo surgical treatment; (2) Aged 18-80 years; (3) Confirmed diagnosis of colorectal cancer by clinical examination; (4) CT scan of abdomen (unenhanced or enhanced) was performed in our hospital within 1 month before surgery; (5) Long-term adherence to treatment and follow-up can be maintained.

Exclusion criteria

Exclusion criteria: 1. Case-control study exclusion criteria: (1) Diseases of the spine and limbs; (2) Serious organ dysfunction such as heart, lung, liver and kidney; (3) History of previous abdominal surgery; (4) Those with cognitive impairment and mental illness. 2. Exclusion criteria for cohort studies: (1) There is sarcopenia at the time of admission; (2) Patients with multiple primary malignant tumors; (3) Complicated with serious organ dysfunction such as heart, lung, liver, and kidney; (4) Combined with spinal and limb bone and joint diseases; (5) History of previous abdominal surgery; (6) Combined distant metastasis; (7) Those with cognitive dysfunction and mental illness.

Design outcomes

Primary

Measure	Time frame
Body mass index;Prognostic nutritional index;Neutrophil/lymphocyte ratio;Systemic immune inflammation index;Skeletal muscle mass index;Calf circumference;Tumor markers;	—

Secondary

Measure	Time frame
Albumin;Hospital stay;Mortality;	—

Countries

China

Contacts

Public ContactWang Min

Southwest Medical University

12110875@qq.com+86 18716135801

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026