Depression
Conditions
Sponsors
Beijing Chaoyang Hospital Affiliated to Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: 1. Clinically diagnosed as depressive disorder without psychotic symptoms by a psychiatrist practitioner, and meet the diagnostic criteria for depressive disorder without psychotic symptoms in the Diagnostic and Statistical Manual of Mental Disorders IV (DSM-IV); 2. The total score of the Montgomery-Asherberg Depression Rating Scale (MARDS) is >=22 points, and the suicide item score is >=1 point, but they do not accept the recommendation of referral to a psychiatric hospital and still require treatment at the study site; 3. Aged 18-64 years, gender is not limited; 4. Be able to understand the content of the scale and cooperate with the assessment; 5. Sign the informed consent for the study and be able to follow up.
Exclusion criteria
Exclusion criteria: 1. Patients with previous history of alcohol and drug dependence and acute poisoning; history of illegal drug abuse; patients with psychotic disorder, bipolar disorder, and obsessive-compulsive disorder; 2. The current main diagnosis is not patients with depressive disorder; 3. Those who currently have a high risk of suicide: such as suicide attempts, recent suicide attempts; and no family caregivers; 4. Pregnant or lactating patients; 5. The use of ketamine, esketamine, or midazolam is contraindicated; 6. Patients who have used ECT or NMDA receptor antagonists within the past 6 months; 7. Patients with respiratory diseases, hypertension, or other serious physical diseases that are difficult to control, such as: patients with severe cardiovascular disease and hyperthyroidism, increased intracranial pressure, cerebral hemorrhage, and glaucoma.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cognitive function;social function; | — |
Secondary
| Measure | Time frame |
|---|---|
| depressive symptom; | — |
Countries
China
Contacts
Public ContactMa Ke
Beijing Chaoyang Hospital Affiliated to Capital Medical University
Outcome results
None listed