a clinical trial of ketogenic diet in the treatment of autosomal dominant polycystic kidney disease

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100054284

Enrollment

Unknown

Registered

2021-12-12

Start date

2020-06-01

Completion date

Unknown

Last updated

2022-11-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

autosomal dominant polycystic kidney disease (ADPKD)

Interventions

Experimental group:ketogenic diet

Control group:high-quality protein diet

Eligibility

Sex/Gender

All

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1. Diagnosed ADPKD patients. 2. Aged between 18-50 years, light manual laborers. 3. Blood pressure = 750ml, eGFR >= 60ml/min. 6. Subjects signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Inborn errors of metabolism. 2. Diseases of important organs, including: history of pancreatitis, active gallbladder disease, moderate to severe liver damage, frequent gout, fat wasting disorder, severe heart and lung diseases, etc. 3. Diabetes, malnutrition, intolerance to ketogenic diet, unable to take care of themselves, and unable to follow up on time. 4. Pregnant patients, or those who have pregnancy plans.

Design outcomes

Primary

Measure	Time frame
total kidney volume;kidney function;blood ketone body level;urine ketone body level;weight;blood glucose level;blood lipid level;	—

Secondary

Measure	Time frame
blood routine test;liver biochemical test;glycated hemoglobin;urine protein-creatinine ratio;	—

Countries

China

Contacts

Public ContactLiu Chunyan

15541117239@163.com+86 17709870388

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026