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The evaluation value of myeloid cell trigger receptor (TREM) in the prognosis judgment of idiopathic facial nerve palsy and the clinical research of micro-needle knife combined with acupuncture intervention

The evaluation value of myeloid cell trigger receptor (TREM) in the prognosis judgment of idiopathic facial nerve palsy and the clinical research of micro-needle knife combined with acupuncture intervention

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100054280
Enrollment
Unknown
Registered
2021-12-12
Start date
2021-12-13
Completion date
Unknown
Last updated
2022-11-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

idiopathic facial nerve palsy

Interventions

Experimental group:Microneedle knife combined with acupuncture
Control group:Conventional acupuncture

Sponsors

Zhejiang Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria for Bell's palsy; 2. Accept standard western medicine treatment; 3. Aged 18-75 years, the lesion is on one side, and the disease duration is less than 3 months; 4. Voluntarily participate in this study and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with central facial neuritis and peripheral facial neuritis secondary to other diseases (trauma, tumor, otitis media, postoperative acoustic neuroma, facial neuroma, Guillain-Barre syndrome, etc.); those with a history of facial paralysis with sequelae; 2. Patients with severe primary diseases such as diabetic neuropathy, heart, cerebrovascular, liver, kidney, lung and hematopoietic system, and mentally ill patients with low blood and coagulation mechanisms; patients with a history of acupuncture and haemorrhage; 3. Patients with Lyme disease, hemifacial spasm, pregnant or breastfeeding women and those with allergic constitution.

Design outcomes

Primary

MeasureTime frame
House-Brackmann facial nerve function rating scale;

Secondary

MeasureTime frame
Immune-inflammation-related indicators;Facial electrograph examination;Grading scale of facial paralysis;Facial disability index scale;Anxiety self-rating scale;Self-rating depression scale;SF-36 Quality of life assessment scale;

Countries

China

Contacts

Public ContactChen Yidan

Zhejiang Hospital

chenyidan0908@vip.126.com+86 13221067998

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026