Application study of ropivacaine hydrochloride and ketorolac tromethamine for postoperative analgesia after nasal endoscopy

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100054272

Enrollment

Unknown

Registered

2021-12-12

Start date

2021-12-12

Completion date

Unknown

Last updated

2022-11-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Group A:Pre-operative application of aminotriol ketorolac and post-operative application of ropivacaine hydrochloride soaked sponge to fill the operative cavity

Group B:Postoperative application of Ropivacaine Hydrochloride soaked sponge to fill the operative cavity

Group C:Postoperative application of saline-soaked sponges to fill the operative cavity

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients who need endoscopic nasal surgery; 2. Patients who need bilateral nasal packing after operation; 3. ASA classification: I-II level; 4. BMI index is 19-28 kg/m^2.

Exclusion criteria

Exclusion criteria: 1. Patients with allergic rhinitis and nasal tumors; 2. Patients with other cardiovascular and cerebrovascular diseases such as liver and kidney insufficiency, coagulation dysfunction, hypertension, and poorly controlled diabetes; 3. Those with a history of peptic ulcer.

Design outcomes

Primary

Measure	Time frame
Numerical rating scale pain score;	—

Secondary

Measure	Time frame
Time and number of additional rescue analgesics for the first time;Incidence of postoperative adverse reactions (nausea, vomiting, headache);	—

Countries

China

Contacts

Public ContactSima Guoqi

smgq73@163.com+86 13957308970

Outcome results