Ischemic retinopathies
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. The first part: (1) Children with retinopathy of prematurity (ROP): 1) Gender is not limited, aged less than 18 years; 2) Children who meet the diagnosis of ROP; 3) Voluntary participation in this study, informed consent signed by the guardians of the children. (2) Control group: 1) Sex, age, gestational age at birth, birth weight, and corrected gestational age were matched to the ROP group; 2) Voluntarily participate in this study, and the guardians of the children should sign the informed consent. 2. The second part: (1) Patients with diabetic retinopathy (DR): 1) Gender is not limited, aged over 18 years; 2) DR patients; 3) Voluntarily participate in this study and sign the informed consent. (2) Control group: 1) Gender- and age-matched senile cataract patients; 2) Voluntarily participate in this study and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. The first part: (1) Children with ROP: 1) Children with other eye diseases (except congenital cataract), such as morning glory syndrome; 2) Those with a history of recent surgery and trauma; 3) Those with unstable vital signs; 4) Those deemed inappropriate by the researchers. (2) Control group: 1) Children with eye diseases (except congenital cataracts), such as FEVR, Coats disease, morning glory syndrome, etc.; 2) Retinal detachment or retinal neovascularization caused by various reasons within one year after sample collection; 3) Those with unstable systemic vital signs. 2. The second part: (1) DR patients: 1) Those with a history of surgery or trauma in the past 6 months; 2) Patients with other eye diseases (except senile cataract, refractive error), such as AMD; 3) Those with unstable vital signs; 4) Those deemed inappropriate by the researchers. (2) Control group: 1) With a history of diabetes; 2) Those with a history of surgery or trauma in the past 6 months; 3) Patients with other eye diseases (excluding refractive errors), such as vitreous hemorrhage, AMD, etc.; 4) Those with unstable vital signs; 5) Those deemed inappropriate by the researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Protein;Carbohydrate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Demographic characteristics;Disease severity; | — |
Countries
China
Contacts
Shenzhen Eye Hospital