Cervical cancer
Conditions
Interventions
SLNB).
Gold Standard:Systematic pelvic lymph node dissection, and routine pathological examination of each dissected lymph node.
lymph 
(72 
patients 
nanocarbon 
SLNB 
and 
72 
ICG 
Sponsors
National Cancer Center/Peking Union Medical College Cancer Hospital, Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Diagnosis of cervical squamous cell carcinoma, adenocarcinoma and adenosquamous carcinoma by pathological biopsy; 2. The clinical stage is IB1 (FIGO 2018); 3. Whole body imaging (enhanced chest-abdominal-pelvic CT or PET-CT) assesses no distant metastasis; 4. Aged 18-70 years; 5. Physical strength score ECOG<=2 points, can tolerate extensive hysterectomy and pelvic lymph node dissection; 6. No obvious heart, liver, kidney chronic disease or dysfunction, and no history of other malignant tumors; 7. Voluntarily participate in the study and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Residual cervical cancer; 2. The pathological type is small cell carcinoma, neuroendocrine carcinoma and other special types; 3. Those who have received radiotherapy or chemotherapy before enrollment; 4. Allergic constitution, allergic to iodine; 5. ICG skin test positive; 6. Patients deemed unsuitable for inclusion by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall sentinel node detection rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Bilateral sentinel node detection rate;Number of detected sentinel nodes;Location of sentinel node;Sensitivity of sentinel node biopsy;False negative rate of sentinel lymph node biopsy;Negative predictive value of sentinel lymph node biopsy;Duration of operation;Intraoperative bleeding volume;Tracer allergy;Operative complications;Low volume metastasis rate of lymph node; | — |
Countries
China
Contacts
Public ContactLi Bin
Outcome results
None listed