End-tidal carbon dioxide partial pressure to assess the value of passive leg-raising test in predicting volume responsiveness in patients with septic shock

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100054204

Enrollment

Unknown

Registered

2021-12-11

Start date

2021-12-11

Completion date

Unknown

Last updated

2022-11-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Septic shock

Interventions

Gold Standard:Cardiac output.

Index test:PETCO2.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Septic shock patients; 2. Aged >= 18 years; 3. Informed consent.

Exclusion criteria

Exclusion criteria: 1. Contraindication of fluid rehydration test (evidence of heart failure, acute coronary syndrome, cardiogenic shock and volume overload); 2. Contraindications of femoral artery catheterization and leg lifting; 3. Pregnancy; 4. Refusal of PiCCO catheterization by patients or family members.

Design outcomes

Primary

Measure	Time frame
AUC under ROC (Area under Receiver Operating Characteristic Curve);ACC(Accuracy);SEN(Sensitivity);SPE(Specificity);	—

Countries

China

Contacts

Public ContactLiu Yan

People's Hospital of Xinjiang Uygur Autonomous Region

58096557@qq.com+86 13899822871

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026