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The effect of esketamine on preventing postpartum depression in women after cesarean delievery

The effect of esketamine on preventing postpartum depression in women after cesarean delievery

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100054199
Enrollment
Unknown
Registered
2021-12-11
Start date
2022-01-01
Completion date
Unknown
Last updated
2022-11-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postpartum depression

Interventions

Control group:Normal saline

Sponsors

Fujian Provincial Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-40 years; 2. ASA I-III; 3. Singleton pregnancy at full-term( > 37 weeks); 4. Prepare to cesarean section.

Exclusion criteria

Exclusion criteria: 1. Prenatal mental disorder; 2. Patients with hypertension or risk of elevated intracranial pressure; 3. Patients with pre-eclampsia and eclampsia; 4. Patients with hyperthyroidism; 5. Patients with placenta previa, placental abruption, and placenta accreta; 6. Allergy to esketamine; 7. Patients with incomplete medical records; 8. Unable or unwilling to coorporate the questionnaires and clinical examinations.

Design outcomes

Primary

MeasureTime frame
EPDS(Edinburgh Postnatal Depression Scale) score;

Secondary

MeasureTime frame
NRS(Numerical Rating Scale) score;PSQ(Pain Sensitivity Questionnaire) score;5-HT;

Countries

China

Contacts

Public ContactWu Xiaodan

Fujian Provincial Hospital

wxiaodan@sina.com+86 13055291720

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 6, 2026