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Effect of positive pressure and non-positive pressure ventilation on gastric volume during induction of general anesthesia in laparoscopic surgery: a randomized controlled trial

Effect of positive pressure and non-positive pressure ventilation on gastric volume during induction of general anesthesia in laparoscopic surgery: a randomized controlled trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100054193
Enrollment
Unknown
Registered
2021-12-10
Start date
2021-12-10
Completion date
Unknown
Last updated
2022-11-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric insufflation

Interventions

Positive pressure group:Positive airway pressure assisted ventilation with mask
Non-positive pressure group:Fasten the mask without positive airway pressure assisted ventilation

Sponsors

Nanfang Hospital of Southern Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Voluntarily signed informed consent; 2. ASA I-II; 3. Aged 18-65 years (inclusive 18 years old); 4. Mallampati grades I-III; 5. Two or less independent risk factors for mask dyspnea (aged > 55 years, BMI > 26 kg/m^2, history of snoring, beard, and no teeth); 6. BMI = 8 h, no drinking time >= 2 h; 8. No drugs affecting gastrointestinal motility were taken 1 day before surgery.

Exclusion criteria

Exclusion criteria: 1. Allergic to the drugs involved in the study protocol; 2. Difficult airway, risk of upper airway obstruction; 3. Cardiopulmonary dysfunction, cerebrovascular disease; 4. Gastroesophageal reflux disease, intestinal obstruction, esophageal or gastrointestinal trauma or surgical history; 5. Diabetes mellitus; 6. Pregnancy.

Design outcomes

Primary

MeasureTime frame
Change of the cross-sectional area (CSA) of gastric antrum;

Secondary

MeasureTime frame
Arterial partial pressure of oxygen;Arterial partial pressure of carbon dioxide;pH;Bicarbonate;Heart rate;Mean arterial pressure;Saturation of pulse oxygen;Incidence of reflux of gastric contents;

Countries

China

Contacts

Public ContactQin Zaisheng

Nanfang Hospital of Southern Medical University

QZSMZK@163.com+86 13434243868

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 10, 2026