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Effects of different methods of deflating tracheal tube cuff on cough reflex during extubation: a randomized clinical trial

Effects of different methods of deflating tracheal tube cuff on cough reflex during extubation: a randomized clinical trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100054089
Enrollment
Unknown
Registered
2021-12-08
Start date
2022-03-18
Completion date
Unknown
Last updated
2022-11-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

operations under general anesthesia with oral endotracheal intubation

Interventions

experimental group :deflating slowly with cuff pressure gauge
Control Group:deflating using 10ml syringe within 1s
Syringe group:deflating using 10ml syringe at 1ml/s' speed

Sponsors

Department of Anesthesiology, General Hospital of Eastern Theater Command, Jinling School of Clinical Medicine, Nanjing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Gender is not limited; 2. Aged 18-65 years; 3. ASA I-II grade; 4. The operation time is less than or equal to 3h.

Exclusion criteria

Exclusion criteria: 1. Refuse to sign the informed consent; 2. BMI= 30kg m^2; 3. Mallampati classification III to IV; 4. Preoperative sore throat, hoarseness, cough, pharyngeal mucosal bleeding; asthma; COPD; 5. Mental illness; 6. Brain surgery; 7. Nasal intubation; 8. ENT surgery; 9. Smoking.

Design outcomes

Primary

MeasureTime frame
Incidence and severity of cough reflex;

Secondary

MeasureTime frame
the incidence and severity of postoperative airway complications occured within 48 hours;

Countries

China

Contacts

Public ContactDuan Manlin

Department of Anesthesiology, General Hospital of Eastern Theater Command, Jinling School of Clinical Medicine, Nanjing Medical University

dml1200@126.com+86 13705184501

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 10, 2026