Skip to content

Drive pressure is the effect of guided mechanical ventilation on pulmonary complications after spinal posterior surgery in middle-aged and elderly people

Drive pressure is the effect of guided mechanical ventilation on pulmonary complications after spinal posterior surgery in middle-aged and elderly people

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100054078
Enrollment
Unknown
Registered
2021-12-08
Start date
2021-12-20
Completion date
Unknown
Last updated
2022-11-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with posterior spinal surgery

Interventions

group P :Drive the pressure for titrating the PEEP
group C :Fixed PEEP value was 5cmH2O

Sponsors

The First Affiliated Hospital of Nanchang University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Aged >= 40 years, and the gender is not limited; 2. Subjects underwent posterior spinal surgery in prone position (operation time > 2 hours); 3. ASA class I-II, cardiac function class I-II (NYHA class).

Exclusion criteria

Exclusion criteria: 1. Pregnant or breastfeeding women; 2. According to the judgment of the investigator, the subjects have other factors that may cause them to be forced to terminate the study halfway, such as other serious diseases (including mental diseases) that require concomitant treatment, severely abnormal laboratory test values, and family or social factors, which may affect the study. to the situation of subject trial data collection; 3. Investigators believe that they are not suitable for inclusion, such as patients with acute lung injury or acute respiratory distress syndrome in the past three months, cardiac NYHA class IV, chronic renal failure, liver failure, etc.; 4. Body mass index (BMI) >= 35kg/m^2; 5. Acute infection, sepsis within 2 weeks before surgery; history of chronic obstructive pulmonary disease; 6. History of thoracic or emergency surgery; 7. progressive neuromuscular disease; 8. Acute lung injury, acute respiratory distress syndrome, those who need long-term ventilator-assisted ventilation after operation; 9. Patients with poorly controlled hypertension.

Design outcomes

Primary

MeasureTime frame
Postoperative pulmonary complications;

Countries

China

Contacts

Public ContactOuyang Ru

The First Affiliated Hospital of Nanchang University

zhuwanbin999@163.com+86 13672235150

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026