A double-blind, randomized, controlled, prospective observational clinical study of the application of adsorption technology during CPB in patients with infective endocarditis

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100054076

Enrollment

Unknown

Registered

2021-12-08

Start date

2021-12-01

Completion date

Unknown

Last updated

2022-11-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infectve endocardits

Interventions

Extracorporeal circulation group:Cardiopulmonary bypass

CPB+ HA380 hemoperfusion group:CPB+ HA380 hemoperfusion device

Eligibility

Sex/Gender

All

Age

No minimum to 90 Years

Inclusion criteria

Inclusion criteria: 1. Patients between the ages of 18-75, regardless of gender; 2. CPB time is greater than 1.5 hours; 3. Be able to understand and sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Pregnant, perinatal pregnant women; 3. Coagulation disorders; 4. Have a history of serious heart, brain, lung, kidney and other diseases within 3 months before surgery; 5. Oral anticoagulants are required in the perioperative period; 6. History of special and rare diseases, history of genetic diseases.

Design outcomes

Primary

Measure	Time frame
Change levels of inflammation markers;	—

Secondary

Measure	Time frame
Related inflammation markers;Coagulation parameters;Perioperative complications;	—

Countries

China

Contacts

Public ContactDeng Li

Gaozhou People's Hospital Affiliated to Guangdong Medical University

dengli_198118@163.com+86 15004684072

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026