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Detection and screening of pain related serum markers

Detection and screening of pain related serum markers

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100054075
Enrollment
Unknown
Registered
2021-12-08
Start date
2021-12-01
Completion date
Unknown
Last updated
2022-11-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain after stroke and spinal cord injury

Interventions

Stroke group:None
control group:None

Sponsors

Jiangsu Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Aged 20-80 years; 2. Stroke: in line with the diagnostic points formulated by the Neurology Branch of the Chinese Medical Association and the Cerebrovascular Group of the Neurology Branch of the Chinese Medical Association in 2019; the first unilateral onset; the experimental group had hemiplegic shoulder pain, and the pain degree VAS>3 points; hemiplegic shoulder pain Comply with the relevant standards of the "Chinese Rehabilitation Medicine Diagnosis and Treatment Standards"; 3. Spinal cord injury: The diagnosis was in accordance with the international standard for neurological classification of spinal cord injury (revised in 2011); the lower extremity neuropathic pain in the experimental group, the pain degree VAS > 3 points; 4. Confirmed by CT/MRI examination; 5. Patient informed consent.

Exclusion criteria

Exclusion criteria: 1. Coma, unclear consciousness, critical condition, unwilling or unable to cooperate; 2. Women who have been pregnant or are about to be pregnant recently; 3. Other factors affecting information collection, such as mental history; 4, There are infectious diseases, rheumatic immune system diseases, such as respiratory tract, urinary tract, skin and soft tissue infection, systemic lupus erythematosus, Sjogren syndrome and so on. 5. Pain in other parts of the body.

Design outcomes

Primary

MeasureTime frame
Nerve growth factor;Substance P;Prostaglandin E2;Tumor necrosis factor- a;Interleukin-1 ß;Interleukin-2;interleukin-6;Interleukin-10;Calcitonin gene related peptide;Bradykinin;Simplified McGill Pain Questionnaire;Magnetic resonance imaging;

Secondary

MeasureTime frame
Passive painless range of motion;Modified Ashworth score;Neuropathic pain assessment scale;Sympathetic dysfunction assessment;Brunnstrom stage;ASIA assessment scale for spinal cord injury;Barthel index;Self rating Anxiety Scale;Self rating Depression Scale;

Countries

China

Contacts

Public ContactMeng Dianhuai

Jiangsu Provincial People's Hospital

dhdream@126.com+86 13813917337

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026