Pain after stroke and spinal cord injury
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 20-80 years; 2. Stroke: in line with the diagnostic points formulated by the Neurology Branch of the Chinese Medical Association and the Cerebrovascular Group of the Neurology Branch of the Chinese Medical Association in 2019; the first unilateral onset; the experimental group had hemiplegic shoulder pain, and the pain degree VAS>3 points; hemiplegic shoulder pain Comply with the relevant standards of the "Chinese Rehabilitation Medicine Diagnosis and Treatment Standards"; 3. Spinal cord injury: The diagnosis was in accordance with the international standard for neurological classification of spinal cord injury (revised in 2011); the lower extremity neuropathic pain in the experimental group, the pain degree VAS > 3 points; 4. Confirmed by CT/MRI examination; 5. Patient informed consent.
Exclusion criteria
Exclusion criteria: 1. Coma, unclear consciousness, critical condition, unwilling or unable to cooperate; 2. Women who have been pregnant or are about to be pregnant recently; 3. Other factors affecting information collection, such as mental history; 4, There are infectious diseases, rheumatic immune system diseases, such as respiratory tract, urinary tract, skin and soft tissue infection, systemic lupus erythematosus, Sjogren syndrome and so on. 5. Pain in other parts of the body.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Nerve growth factor;Substance P;Prostaglandin E2;Tumor necrosis factor- a;Interleukin-1 ß;Interleukin-2;interleukin-6;Interleukin-10;Calcitonin gene related peptide;Bradykinin;Simplified McGill Pain Questionnaire;Magnetic resonance imaging; | — |
Secondary
| Measure | Time frame |
|---|---|
| Passive painless range of motion;Modified Ashworth score;Neuropathic pain assessment scale;Sympathetic dysfunction assessment;Brunnstrom stage;ASIA assessment scale for spinal cord injury;Barthel index;Self rating Anxiety Scale;Self rating Depression Scale; | — |
Countries
China
Contacts
Jiangsu Provincial People's Hospital