The effect of computer-assisted cognitive training combined with transcranial direct current stimulation in the treatment of cognitive dysfunction after ischemic stroke and the influence of cerebral hemodynamics

Observation on the effect of computer-assisted rehabilitation combined with tDCS in the treatment of cognitive dysfunction after stroke

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100054063

Enrollment

Unknown

Registered

2021-12-08

Start date

2021-12-06

Completion date

Unknown

Last updated

2022-11-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischemic stroke

Interventions

Routine Artificial Cognitive Rehabilitation Group:Cognitive rehabilitation training

Transcranial direct current stimulation treatment group:Transcranial direct current stimulation therapy

Computer Aided Cognitive Training Group:Computer aided cognitive training

Combination Therapy Group:Computer-assisted cognitive training combined with transcranial direct current stimulation therapy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Meet the relevant diagnostic criteria of the included diseases and be confirmed by head CT or MRI; 2. Right-handed patients with age >=18 years old, no gender restrictions, native language Chinese, and education for 6 years or more; 3. Those with mild to moderate cognitive impairment. MOCA scale score <26 points; 4. Informed consent, volunteer experiment.

Exclusion criteria

Exclusion criteria: 1. Those with unstable vital signs (BP, heart rate, etc. exceeding normal); 2. Combined with severe diagnosed primary diseases of the heart, liver, kidney, hematopoietic, and metabolic systems that are not suitable for cognitive rehabilitation; 3. Patients with coma, severe cognitive dysfunction, severe motor dysfunction, complete aphasia or sensory aphasia who cannot actively cooperate with rehabilitation training; 4. Obvious cognitive impairment before stroke; 5. Complete damage to the left frontal lobe; 6. Patients with implanted devices with metal parts in the stimulation area; patients with hyperalgesia in the stimulation area; patients with local skin damage or inflammation; 7. Obvious depression SDS score >= 53 points or SAS score >= 50 points; 8. Patients who participate in other clinical trials may affect the final assessment results.

Design outcomes

Primary

Measure	Time frame
Montreal cognitive assessment, MOCA;	—

Secondary

Measure	Time frame
Instrumental Activities of Daily Living Scale, IADL;	—

Countries

China

Contacts

Public ContactZhao Ziqi

Department of Rehabilitation Medicine, West China Hospital, Sichuan University

920466450@qq.com+86 15756355207

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 8, 2026