Pulmonary disease
Conditions
Interventions
experimental group:Balloon blocking bronchus in percutaneous lung puncture biopsy in patients with severe invasive mechanical ventilation
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 79 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 80 years; 2. Patients with tracheal intubation and mechanical ventilation; 3. Imaging studies suggest that there are obvious lesions (including but not limited to consolidation, patches, nodules, masses, cavities, etc.) or diffuse interstitial lung disease of unknown cause in the outer bands of both lungs; 4. No pulmonary etiology or etiological basis was found in routine examination, or the patient's pulmonary disease progression could not be explained by existing clinical data.
Exclusion criteria
Exclusion criteria: 1. The patient or family member refuses to participate; 2. The blood oxygen partial pressure under optimal mechanical ventilation is less than 60mmHg; 3. Platelets 1.5, or FIB < 1 g/L; 4. Pregnant patients; 5. Other conditions that the clinician thinks cannot be punctured.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Puncture success rate;The incidence of operation-related complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| Positive rate of puncture specimen results;Etiological test results;Invasive mechanical ventilation time;Length of ICU stay;ICU mortality; | — |
Countries
China
Contacts
Public ContactWang Ye
West China Hospital, Sichuan University
Outcome results
None listed